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Endocrine factors significantly contribute to migraine pathogenesis, as evidenced by the pronounced gender difference, with women being more frequently affected

DOI:10.1038/srep09392 [ Links ] 46

HIF-1 is a regulator of galectin-3 expression in the intervertebral disc

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Neurological symptoms may take 36 months to fully resolve, and some nerve damage may be permanent if treatment was delayed beyond 12 months